MTB32A Antigen of mycobacterium tuberculosis with inactivated active site and fusion proteins thereof

Antigène MTB32A de mycobacterium tuberculosis ayant un site actif inactivé et protéines de fusion comprennant ledit antigène.

MTB32A Antigen aus Mycobakterium Tuberculosis mit inaktivierter protease Aktivität und Fusionsproteine die das Antigen enthalten

Abstract

The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.

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