Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin

Kinases de protéine impliquée dans l'apoptose, inhibiteurs et activateurs de celui-ci pour une utilisation dans des compositions pharmaceutiques et en médecine prédictive

Death-associated protein kinases, inhibitors and activators thereof for use in pharmaceutical compositions and in predictive medicine

Abstract

The present invention concerns pharmaceutical compositions comprising DAPK or inhibitors or activators thereof in the treatment, prevention, amelioration and delay of cancer or in the induction or suppression of inflammation as well as predictive methods for determining the risk of developing cancer in a subject, for determining the overall and disease-free survival time of a subject suffering from cancer and for deciding a personalized therapy for a subject suffering from cancer. Further, kits in order to perform said predictive methods are described.

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